Thyroid Diseases in brief…. part 1. 

#Hyperthyroidism #Grave’sdisease 

Thyroid Diseases mainly consist :

1. Hyperthyroidism

2. Hypothyroidism

3. Thyroiditis


Hyperthyroidism is the syndrome resulting from excess of thyroid hormones. The term Hyperthyroidism indicates thyroid gland overactivity resulting in thyrotoxicosis, but thyrotoxicosis can occur without hyperthyroidism when stored hormone is released from a damaged thyroid or when excess thyroid hormone is taken.

Common Causes of thyrotoxicosis – 

1. Grave’s disease – Autoimmune disorder in which thyroid stimulating immunoglobulin  (TSI) binds to & stimulate thyroid stimulating hormone  (TSH) receptor on thyroid cell membrane resulting in excessive synthesis and secretion of thyroid hormone.

2. Toxic adenoma – monoclonal autonomously secreting benign thyroid tumor

3. Toxic multi-nodular goiter – multiple  monoclonal autonomously secreting benign thyroid tumor

4. Exogenous thyroid hormone – excess exogenous thyroid hormone

Clinical features:


Symptoms – weight loss,  increased appetite,  heat intolerance & sweating,  fatigue & weakness,  hyperactivity, irritability, dysphoria, insomnia,  depression, diarrhoea,  polyuria,periodic paralysis

Signs – tremor, hyper-reflexia, warm moist heat, hairloss, muscle weakness,  cardiac failure

Diagnosis done by – 

1. Serum T3 ,T4

2. Thyroid radioiodine uptake

3. Thyroid scan

4. Serum thyroperoxidase (TPO)

Management: of Grave’s disease –

1. Antithyroid drugs

2. Radioactive iodine

3. Subtotal thyroidectomy.

By Prashastii Patel

Dr. Prashastii Patel is a Physical Therapist & a certified fitness trainer. Being in the medical field, she loves to share information and knowledge about Health, Fitness and Wellness here on this blog. Dr. Prashasti Patel is the Founder of Kaushalyam Fitness & Wellness Center. She also runs another blog in the category of Fashion, Beauty & Lifestyle. She has also done master in Reiki Healing. She treats people with Reiki also.

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